We have tutorials on setting up IMAP/POP accounts for major e-mail clients, including Thunderbird, Outlook, Android and iOS.
Most clients will require a manual setup.
Please click here for our web page on what server names and ports to use.
Remember to always mark the option to "Require authentication" (sometimes referred to as "My server requires SMTP authentication").
Also note that IMAP is recommended rather than POP, as it´s a protocol made to support several devices accessing one same account, with all folders synced at our server, which also guarantees that our backups will be executed.